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artP [2017-07-25 10:35:04]
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artP [2017-07-25 10:35:04]

high affinity arginine ABC transporter (ATP-binding protein)
locus
BSU23980
pI
5.09
mw
28.16 kDa
protein length
255 aa Sequence Blast
gene length
765 bp Sequence Blast
function
arginine uptake
product
high affinity arginine ABC transporter (ATP-binding protein)
essential
no
synonyms
yqiX

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.2|Uptake of amino acids]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.4|Biosynthesis/ acquisition of arginine]
  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    2,492,029 → 2,492,796

    The protein

    Protein family

  • bacterial solute-binding protein 3 family (according to Swiss-Prot)
  • Structure

  • [PDB|2Q2C] (Geobacillus stearothermophilus)
  • [SW|Localization]

  • attached to the membrane via [protein|62BD291B91DB0358754957D84A1F3636C247A697|ArtQ] [Pubmed|10092453]
  • extracellular (signal peptide) [Pubmed|18957862], membrane [Pubmed|18763711]
  • Expression and Regulation

    Operons

    genes
    [gene|8D9529D46E11D8B2826A98642706ADCBE1E3434A|artP]-[gene|62BD291B91DB0358754957D84A1F3636C247A697|artQ]-[gene|6882EF93EC82872B25C88104F62D6603D2514890|artR]
    description
    [Pubmed|12107147]

    regulatory mechanism

  • [protein|F4097349A563503468A2A14F062AEAC532C7917A|YlxR]: regulation, [pubmed|30355672], in [regulon|F4097349A563503468A2A14F062AEAC532C7917A|YlxR regulon]
  • regulation

  • repressed by casamino acids [Pubmed|12107147]
  • induced in the absence of [protein|F4097349A563503468A2A14F062AEAC532C7917A|YlxR] [pubmed|30355672]
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    Biological materials

    Mutant

  • MGNA-C381 (yqiX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2379 NBRP B. subtilis, Japan]
  • References

  • 10092453,18957862,12107147,18763711,11423008,23038252